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Biography
Education
09/2008- 01/2013, Ph.D., Organic Chemistry, Tsinghua University, China
09/2005-07/2008, M.S., Medical Chemistry, Shenyang Pharmaceutical University, China
09/2001-07/2005, B.S., Pharmaceutical Engineering, Qiqihar University, ChinaProfessional Experience
2019/08-present, Lecturer, Tsinghua Shenzhen International Graduate School, China;
2018/03-2019/08, Lecturer, Graduate School at Shenzhen, Tsinghua University, China;
2015/07-2017/, Postdoctoral associate, Dalian Institute of Chemical Physics, CAS, China and South University of Science and Technology of China, China;
2013/03-2015/07, Research Fellow, South University of Science and Technology of China, China;
Additional Positions
Opening
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Current Courses
Synthetic Organic Chemistry
Organic Spectroscopy
Medicinal Chemistry Experiments
Master’s & Ph.D. Advising
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Research Interests
Design, Synthesis and Activity Research of Multi-target Anti-tumor Small Molecules Based on AI.
Chiral Drug-Oriented Asymmetric Catalytic Synthetic Methodology
Projects
National Natural Science Foundation of China (21602098);
Research Output
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Selected Publications
[1]Jin-Shun Lin #, Tao-Tao Li #, Guan-Yuan Jiao #, Qiang-Shuai Gu, Jiang-Tao Cheng, Ling Lv, and XinYuan Liu*. “Chiral Brønsted Acid-Catalyzed Dynamic Kinetic Asymmetric Hydroamination of Racemic Allenes and Asymmetric Hydroamination of Dienes. Angew. Chem. Int. Ed.2019, 58, 7092. (#Co-first author)
Highlighted in Synfacts2019, 15, 662.
[2]Jin-Shun Lin #, Tao-Tao Li #, Ji-Ren Liu #, Guan-Yuan Jiao, Qiang-Shuai Gu, Jiang-Tao Cheng, Yu-Long Guo, Xin Hong* and Xin-Yuan Liu*.“Cu/Chiral Phosphoric Acid-Catalyzed Asymmetric Three-Component Radical-Initiated 1,2-Dicarbofunctionalization of Alkenes’’. J. Am. Chem. Soc. 2019, 141, 1074. (#Co-first author)
Highlighted in Synfacts2019, 15, 0255.
[3]Fu-Li Wang #, Xiao-Yang Dong #, Jin-Shun Lin#,Yang Zeng, Guang-Yuan Jiao, Qiang-Shuai Gu, Xiang-Qi Guo, Can-Liang Ma, Xin-Yuan Liu*.“Catalytic Asymmetric Radical Diamination of Alkenes. Chem 2017. 3, 979. (#Co-first author)
Highlighted in Chem2017, 3, 919.
[4]Jin-Shun Lin #, Fu-Li Wang #, Xiao-Yang Dong #, Wei-Wei He, Yue Yuan, Su Chen, Xin-Yuan Liu*. “Catalytic Asymmetric Radical Aminoperfluoroalkylation and Aminodifluoromethylation of Alkenes with Fluoroalkylsulfonyl Chlorides: A Versatile Platform for Enantioenriched-Fluoroalkyl Amines”. Nat. Commun.2017,8, 14841. (#Co-first author).
[5]Jin-Shun Lin, Xiao-Yang Dong, Tao-Tao Li, Na-Chuan Jiang, Bin Tan, and Xin-Yuan Liu*. “A Dual-Catalytic Strategy to Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes”. J. Am. Chem. Soc. 2016, 138, 9357.
Highlighted in Synfacts, 2016, 12, 1020.Highlighted in Chin. J. Org. Chem.2016, 36, 2247.
[6]Jin-Shun Lin, Peng Yu, Lin Huang, Pan Zhang, Bin Tan,* and Xin-Yuan Liu*. “Brønsted Acid-Catalyzed Asymmetric Hydroamination of Alkenes: Synthesis of Pyrrolidines Bearing a Tetrasubstituted Carbon Stereocenter”. Angew. Chem. Int. Ed.2015, 54, 7847.
Highlighted in Chin. J. Org. Chem., 2015, 35, 1802.
[7]Zhichao Shi#, Tingting Fan#, Xun Zhang Feng Zhan, Zhe Wang,Lei Zhao, Jin-Shun Lin* and Yuyang Jiang*. “Synthesis of Diversely Substituted Imidazolidines via [3+2] Cycloaddition of 1,3,5-Triazinanes with Donor-Acceptor Aziridines and Their Anti-Tumor Activity”. Adv. Synth. Catal. 2021,363, 2619. (#Co-first author)
Books
Patents
Others
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Awards and Honors
Shenzhen High-level Professional Reserve Talent, Shenzhen, 2020.
The winner of SUSTech Presidential Postdoctoral Fellowship (Top 10%), SUSTech, China. 2017.