谭英

2001年09月-2005年07月，华中师范大学应用化学专业本科毕业

2005年09月-2010年07月，华中师范大学/南开大学化学专业博士

2010年07月-2012年07月，清华大学博士后

2012年10月至今，清华大学深圳研究生院生命与健康学部讲师、副教授

2016年10月-2017年10月，新加坡国立大学访问学者

《Advanced Agrochem》、《VIEW》青年编委。

中国生化制药工业协会重组药物分会专家委员

深圳市药学会分析专业委员会副主任委员

《生物医学与信息学实验（轮转1）》

围绕疾病精准诊疗，建立一系列无创、高灵敏、高特异的疾病诊断体系和装置；发展基于合成生物学和生物正交的药物开发体系，调控和干预生命过程；开发全新的人工智能算法，并应用于多组学研究、疾病诊断和药物设计。主持国家自然基金、深圳市学科布局、深圳市基础研究等项目，参与国家科技部重点研发项目、国家973、国家863等项目。在Nature Commun.、Adv. Funct. Mater.、Chem、JACS、Angewandte、Nat. Mach. Intell.、Small、Biosens. Bioelectron.、Sci. China Chem.等期刊上发表论文150余篇。

[1] Jiayi Shi, Huijing Teng, Ziyi Zhang, Yanping Liu, Dan Gao, Jianglei Di, Zijian Yang, Ping Su,* Ying Tan,* Jianshe Ma. Spatial microfluidic holographic integrated platform for label free and high-dimensional analysis of cancer heterogeneity. Nature Communications. 2025, 16:5890.

[2] Teng Zhang, Ying Feng, Cong-Qiao Xu,* Shina Quek, Junqiao Wang, Jun Li, Ying Tan,* Lixin Wu, and Cheuk-Wai So*. An Atomically Precise Alkynyl-Functionalized Silver–Polyoxotungstate Nanocluster with Sandwiched Three-Layer {Ag13}13+ Cluster Architecture and Enhanced Antitumor Activity. Angewandte Chemie International Edition. 2025, e202508288.

[3] Fan Cao, Hongguang Lin, Chen Zhang, Zhimin Cao, Qingfang Li, Pingxia Wang, Ge Gao, Lin Cheng*, Ying Tan* & Liping Cao*. Coordination-Driven [c2] Daisy Chain of Monofunctionalized Tetraphenylethene-Based Hexacationic Cage and Zinc-Porphyrin Toward Photocatalysis-Assisted Photodynamic Therapy. CCS Chemistry, 2025, DOI: 10.31635/ccschem.025.202505526.

[4] Zheng-Xin Zhou, Yue-Liu-Ting Fu, Chen Zhang, Yuan-Heng Li, Bin-Jun Zhang, Yu-Qing Xiao, Yu-Jie Li, Li-Yan Chen, Li Rao,* Ying Tan,* Wen-Jing Xiao, and Liang-Qiu Lu*. Modular Synthesis of Planar-Chiral Cyclononenes via trans-Retentive Trapping of π‑Allyl-Pd Dipoles. Journal of the American Chemical Society, 2025,  147, 3223−3232.

[5] Ying Feng, Zhilin Zhang, Haowei Zhang, Hui Guo, Chunyan Tan, Naihan Xu,* Ying Tan,* and Yuyang Jiang. Aptamer Proteolysis-Targeting Chimeras (PROTACs): A Novel Strategy to Combat Drug Resistance in Estrogen Receptor α-Positive Breast Cancer. ACS Pharmacology & Translational Science, 2024, 7, 3945-3954.

[6] Yu-Qing Xiao, Kai-Xin Fang, Zhihan Zhang, Chen Zhang, Yu-Jie Li, Bao-Cheng Wang, Bin-Jun Zhang, Yu-Qing Jiang, Miao Zhang, Ying Tan*, Wen-Jing Xiao and Liang-Qiu Lu*, Hyperconjugation-Driven Isodesmic Reaction of Indoles and Anilines: Reaction Discovery, Mechanism Study, and Antitumor Application. Angewandte Chemie International Edition. 2024, e202408426.

[7] Chen Zhang, Junqiao Wang, Hui Chen, Muzi Ouyang, Yuanheng Li, Chunyan Tan, Yuyang Jiang, and Ying Tan*. A Therapeutic Pretargeting Strategy for Triple-Negative Breast Cancer Based on a Bioorthogonal Reaction and a Self-Assembled Peptide. Advanced Functional Materials, 2024, 2313090.

[8] Xiaoqi Xue, Chen Zhang, Xiaolin Li, Junqiao Wang, Haowei Zhang, Ying Feng, Naihan Xu, Hongyan Li, Chunyan Tan, Yuyang Jiang, Ying Tan*. mRNA PROTACs: engineering PROTACs for high-efficiency targeted protein degradation. MedComm. 2024, 5:e478. (封面文章）

[9] Hui Chen, Ying Feng, Feng Liu, Chunyan Tan, Naihan Xu, Yuyang Jiang,** Ying Tan*. Universal smartphone-assisted label-free CRISPR/Cas12a-DNAzyme chemiluminescence biosensing platform for on-site detection of nucleic acid and non-nucleic acid targets. Biosensors and Bioelectronics, 2024, 247, 115929.

[10] Muzi Ouyang, Ying Feng, Hui Chen, Yanping Liu, Chunyan Tan, and Ying Tan*. Recent Advances in Optically Controlled PROTAC, Bioengineering, 2023, 10, 1368.

[11] Dongyang Li, Tianruo Shen, Xiaoqi Xue, Weijie Chen, Wenjun Tao, Weijie Chi, Sheng Hua Liu, Ying Tan*, Xiaogang Liu*, Jun Yin*. Synergistic effects of multiple rotors and hydrogen-bond interactions lead to sensitive near-infrared viscosity probes for live-cell microscopy. Science China Chemistry, 2023, 66: 2329-2338.

[12] Kai Ping Cheng, Wan Xiang Shen, Yu Yang Jiang, Yan Chen, Yu Zong Chen,* Ying Tan*. Deep learning of 2D-Restructured gene expression representations for improved low-sample therapeutic response prediction. Computers in Biology and Medicine. 2023, 164, 107245.

[13] Bao-Cheng Wang, Li Rao, Kai-Xin Fang, Bao-Le Qu, Fen-Ya Xiong, Ying Feng, Ying Tan,* Liang-Qiu Lu,* and Wen-Jing Xiao. Dearomatization-Rearomatization Reaction of Metal-Polarized Aza-ortho-Quinone Methides. Angewandte Chemie International Edition. 2023, e202301592.

[14] Chen Li, Hui Chen, Tingting Fan, Jingru Zhao, Zheng Ding, Zeyu Lin, Shuqing Sun, Chunyan Tan, Feng Liu, Hongtao Jian*, Ying Tan*. A visualized automatic particle counting strategy for single-cell level telomerase activity quantification. VIEW, 2023, 20220078. (cover paper）

[15] Bao-Cheng Wang, Tingting Fan, Fen-Ya Xiong, Peng Chen, Kai-Xin Fang, Ying Tan,* Liang-Qiu Lu,* and Wen-Jing Xiao De Novo Construction of Chiral Aminoindolines by Cu-Catalyzed Asymmetric Cyclization and Subsequent Discovery of an Unexpected Sulfonyl Migration. Journal of the American Chemical Society, 2022, 144, 19932-19941.

[16] Xinyan Zhang, Zhilin Zhang, Xiaoqi Xue, Tingting Fan, Chunyan Tan, Feng Liu, Ying Tan,* and Yuyang Jiang. PROTAC Degrader of Estrogen Receptor α Targeting DNA-Binding Domain in Breast Cancer. ACS Pharmacology & Translational Science, 2022, 5, 1109-1118.

[17] Junyue Chen, Gerile Oudeng, Hongtao Feng, Sixi Liu, Hung-Wing Li, Yi-Ping Ho, Yan Chen,* Ying Tan,* and Mo Yang*. 2D MOF Nanosensor-Integrated Digital Droplet Microfluidic Flow Cytometry for In Situ Detection of Multiple miRNAs in Single CTC Cells. Small, 2022, 2201779. 

2021年深圳市优秀教师

清华大学第九届青年教师教学大赛三等奖

清华大学优秀硕士学位论文指导教师