He Honghui

Dr. He received his PhD in physics from Tsinghua University, Beijing, China, in 2011. He is currently a professor at Tsinghua Shenzhen International Graduate School, Tsinghua University. His research interests include full polarization imaging method and techniques (Mueller matrix polarimetry), interaction between polarized light and turbid media, polarimetric microscopy, endoscopy and their biomedical and clinical applications.

2006/09—2011/07, Department of Physics, Tsinghua University, Ph.D

2002/09—2006/07, Department of Material Sciences and Engineering, Beijing Normal University, B.S

2025/12—present, Tsinghua Shenzhen International Graduate School, Tsinghua University, Professor

2019/08—2025/12, Tsinghua Shenzhen International Graduate School, Tsinghua University, Associate Professor

2017/12—2019/08, Graduate School at Shenzhen, Tsinghua University, Associate Professor

2013/09—2017/11, Graduate School at Shenzhen, Tsinghua University, Lecturer

2011/09—2013/08, Graduate School at Shenzhen, Tsinghua University, Postdoctoral Fellow

1. Youth committee member, Biomedical photonics Committee, Chinese Optical Society (2015-present);

2. Member, Chinese Society of Biomedical Engineering (2015-present);

3. Senior Member, Chinese Optical Society (2015-present);

4. Member, SPIE (International Society for Optical Engineering) (2016-present);

5. Member, Optica (Optical Society of America) (2014-present);

6. Guest editor, Frontiers in Chemistry (2021-present);

7. Guest editor, Applied Sciences (2021-present).

Medical Physics and Physical Therapy

Physical Modeling of Biological Tissues and Medical Applications

Optics, Biomedical optics, Biophotonics

Dr. Honghui He’s research interests include full polarization imaging method and techniques (Mueller matrix polarimetry), interaction between polarized light and turbid media, polarimetric microscopy, endoscopy and their biomedical and clinical applications. He is the committee member of Biomedical Photonics Committee in Chinese Optical Society, the youth editorial board member of Chinese Journal of Lasers, a senior member of Chinese Optical Society, also a member of Chinese Society of Biomedical Engineering, SPIE, and Optica, Guest editor of Journal of Selected Topics in Quantum Electronics, Journal of Innovative Optical Health Sciences. Dr. He published more than 150 scientific research articles including Nature Communications, Science Advances, Light: Science & Applications, Advanced Photonics, Optics Letters, received more than 5500 citations with H-index of 40. Dr. He also co-authored 3 scientific book chapters, licensed more than 10 patents, and has been selected as the World’s Top 2% Scientists 2022, 2023, 2024, 2025. As the Principal Investigator or Co-Principal Investigator, Dr. He received the funding from National Key Scientific Research Instrument Developing Projects, Key Project of National Natural Science Foundation of China, Shenzhen Key Fundamental Research Project.

1. National Key Scientific Research Instrument Developing Project “Wide-Field Two-Photon Microscope” PI of Project 1 “Two-Photon Microscopy Techniques”, Sponsored by Ministry of Science and Technology of the People’s Republic of China (2023-2026).

2. Key Project of NSFC “High-Resolution Microscopic Research on Brain Nerve Fiber Configuration based on Three Dimensional Photoacoustic-Optical Full Polarimetric Imaging” Co-PI, Sponsored by National Natural Science Foundation of China (2024-2028).

3. National Key Scientific Research Instrument Developing Project “Development and Application of Online Analyzer for Identifying Atmospheric Particulate Sources Through Multi-Angle Polarization Scattering Method” PI of Project 3 “Identification of Particles in Air Based on Polarization Scattering Method”, Sponsored by Ministry of Science and Technology of the People’s Republic of China (2016-2021).

4. Disruptive Technology Project for Coordinated Innovation in the Beijing-Tianjin-Hebei Region “High-Resolution Microscopic System for Pathological Diagnosis Based on Adaptive Vectorial Optics” PI (2023-2024).

5. Shenzhen Key Fundamental Research Project “Early Detection and Precision Diagnostic Technique of Gastroenteric Tumor Based on Polarization Imaging” PI, Sponsored by Shenzhen Bureau of Science and Innovation (2021-2024).

1. Yifei Ma†, Zimo Zhao†, Yuanxing Shen†, Binguo Chen, An Aloysius Wang, Yuxi Cai, Ji Qin, Runchen Zhang, Yunqi Zhang, Jiahe Cui, Bangshan Sun, Jiawen Li, Yuzhu Shi, Liangyu Deng, Honghui He*, Lin Luo*, Yonghong He*, Yun Zhang, Ben Dai, Daniel J. Royston, Steve J. Elston, Stephen M. Morris, Martin J. Booth, and Chao He*. “Using optical skyrmions to assess vectorial adaptive optics capabilities in the presence of complex aberrations,” Science Advances 11(40): eadv7904, 2025.

2. Chao He*, Binguo Chen†, Zipei Song†, Zimo Zhao†, Yifei Ma†, Honghui He*, Lin Luo*, Tade Marozsak, An Aloysius Wang, Rui Xu, Peixiang Huang, Jiawen Li, Xuke Qiu, Yunqi Zhang, Bangshan Sun, Jiahe Cui, Yuxi Cai, Yun Zhang, Andong Wang, Mohan Wang, Patrick Salter, Julian AJ Fells, Ben Dai, Shaoxiong Liu, Limei Guo, Yonghong He, Hui Ma, Daniel J. Royston, Steve J. Elston, Qiwen Zhan, Chengwei Qiu, Stephen M. Morris, Martin J. Booth, and Andrew Forbes. “A reconfigurable arbitrary retarder array as complex structured matter,” Nature Communications 16: 4902, 2025.

3. Haohan Zheng, Nan Zeng, Hui Ma, Chao He*, and Honghui He*. “Correction strategy of azimuthal bias in Mueller matrix polarimetry for multilayer birefringent media,” Optics Express 33(9): 19582-19593, 2025.

4. Wei Jiao, Nan Zeng, Rui Hao, Hui Ma, Chao He*, and Honghui He*. “Analysis and optimization of the pixel saturation effect on backscattering Mueller matrix polarimetry,” Optics Letters 50(16): 5069-5072, 2025.

5. Mingzhou Jiang†, Jiahao Fan†, Nan Zeng, Xinxian Zhang, Mickaël Li, Rui Huang, Shaoxiong Liu, Hui Ma, Chao He*, and Honghui He*. “Polarization-assisted multi-domain virtual histopathological staining of tissue specimens,” Optics Letters 50(19): 6016-6019, 2025.

6. Rui Hao, Nan Zeng, Wei Jiao, Honghui He*, Chao He*, and Hui Ma. “Cartesian coordinates transformation for backscattering computational polarimetry,” Optics Express 32(18): 32294-32308, 2024.

7. Zheng Zhang, Nan Zeng, Wei Jiao, Changjiang Mi, Rui Hao, Honghui He*, Chao He*, Hui Ma. “Incidence-modularized 3×4 Mueller matrix polarimetry: A targeted tool with high temporal resolution for in-vivo tissue imaging,” Optics & Laser Technology 179: 111275, 2024.

8. Chao He*†, Jintao Chang†, Patrick S. Salter†, Yuanxing Shen, Ben Dai, Pengcheng Li, Yihan Jin, Samlan Chandran Thodika, Mengmeng Li, Aziz Tariq, Jingyu Wang, Jacopo Antonello, Yang Dong, Ji Qi, Jianyu Lin, Daniel S. Elson, Min Zhang, Honghui He*, Hui Ma*, and Martin J. Booth*. “Revealing complex optical phenomena through vectorial metrics,” Advanced Photonics 4(2): 026001, 2022.

9. Chao He*, Honghui He*, Jintao Chang, Binguo Chen, Hui Ma and Martin J. Booth*. “Polarisation optics for biomedical and clinical applications: a review,” Light: Science & Applications 10: 194, 2021.

10. Honghui He*, Ran Liao, Nan Zeng, Pengcheng Li, Zhenhua Chen, Xi Liu, and Hui Ma*. “Mueller matrix polarimetry - an emerging new tool for characterizing the microstructural feature of complex biological specimen,” Journal of Lightwave Technology 37(11): 2534-2548, 2019.

World’s Top 2% Scientists (2022, 2023, 2024, 2025)

Excellent Master Graduate Student Thesis Supervisor of Tsinghua University (2019, 2021, 2022, 2023, 2024, 2025)

11th Young Faculty Teaching Competition of Tsinghua University, Second Prize.