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Xin-Hui Xing

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  • Biography

    Professor, Deputy Dean of Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School


    Education

    (1)  Ph.D. in Chemical Engineering | Tokyo Institute of Technology, Japan | Apr 1989 – Mar 1992

         Advisor: Prof. Hajime Unno

    (2) M.S. in Applied Chemistry | Utsunomiya University, Japan | Oct 1986 – Mar 1989

         Advisor: Prof. Mitsuo Kuriyama

    (3) B.S. in Applied Chemistry | South China University of Technology, China | Sep 1981 – Jul 1985

     


    Professional Experience

    (1)  Tenured Professor & Executive Vice Dean | Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University | Nov 2019 – Present

    (2) Associate Chair | Department of Chemical Engineering, Tsinghua University | Mar 2009 – Jun 2018

    (3) Director | Institute of Biochemical Engineering, Department of Chemical Engineering, Tsinghua University | Sep 2002 – Jan 2022

    (4) Professor & Doctoral Supervisor (“Hundred Talents Program” Professor) | Department of Chemical Engineering, Tsinghua University | Sep 2000 – Aug 2022

    (5) Lecturer & Associate Professor | Faculty of Engineering, Yokohama National University, Japan | Feb 1998 – Jul 2001

    (6) Assistant Professor | School of Life Science and Technology, Tokyo Institute of Technology, Japan | Apr 1992 – Jan 1998 


    Additional Positions

    Since 12/2019, Deputy director, Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Shenzhen;             

    3/2009-6/2018, Vice Chair, Department of Chemical Engineering, Tsinghua University;


    Opening

    Personal Webpage

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  • Current Courses

    Postdoctoral Fellows (since 2000): 26

    Graduate and Undergraduate Students (since 2000): > 102

    PhD Candidates (since 2001): 26


    Master’s & Ph.D. Advising

  • Research Interests

    Biochemical engineering, enzyme engineering, biobreeding technologies and instrumentation, discovery and bioproduction of carbohydrate drugs and natural bioactive peptides.


    Projects

    Research Output

    Approved Chinese patents: 100

    Books: 4

    Chapters in the Books & Proceedings: 16


  • Selected Publications

    [1] Hai-Hong Chen#, Wei Li#, Yi Wang, Bing Xu, Xi Hu, Xiao-Bing Li, Jun-Yu Liu, Chong Zhang, Can-Yang Zhang, Xin-Hui Xing*. Mining and Validation of Novel Hemp Seed-Derived DPP-IV-Inhibiting Peptides Using a Combination of Multi-omics and Molecular Docking. J Agric Food Chem., 71(23), 9164–9174 (2023). (Cover Article)

    [2] Changge Guan#,*, Jiawei Luo#, Shucheng Li#, Zheng Lin Tan#, Yi Wang, Haihong Chen, Naoyuki Yamamoto, Chong Zhang, Yuan Lu, Junjie Chen and Xin-Hui Xing*. Exploration of DPP-IV Inhibitory Peptide Design Rules Assisted by the Deep Learning Pipeline That Identifies the Restriction Enzyme Cutting Site. ACS Omega, 8, 39662–39672 (2023).

    [3] Yaomeng Yuan, Xihao Liao, Shuang Li, Xin-Hui Xing* & Chong Zhang*. Base editor-mediated large-scale screening of functional mutations in bacteria for industrial phenotypes. SCIENCE CHINA Life Sciences, 67(5), 1051–1060 (2024).

    [4] Long Huang, Wei Hu, Long Qun Huang, Qin Xuan Zhou, Zheng Yang Song, Heng Yu Tao, Bing Xu, Can Yang Zhang*, Yi Wang*, Xin-Hui Xing*. “Hitting Two Birds with One Stone” Design of Intestinal Integrin-Targeting and Redox Homeostasis-Regulating Oral Nanotherapy for Ulcerative Colitis. Science Advances, 10(30), eado7438 (2024).

    [5] Haihong Chen, Wei Li, Wei Hu, Junyu Liu, Canyang Zhang, Yi Wang, Chong Zhang, Xizhen Zhang, Shuo Chen, Qixing Nie*, and Xin-Hui Xing*. Discovery of a novel tetrapeptide as glucose homeostasis modulator with bifunctionalities of targeting DPP-IV and microbiota. iMeta, e70072 (2025).

     


    Books

    Patents

    Others

  • Awards and Honors

    Gold Medal at the 45th Geneva International Inventions and Best International Invention from the National Research Council of Thailand (2017); Award of Advanced Individuals (2017); Fellow, School of Engineering, The University of Tokyo (2018); Outstanding Individual among Returned Overseas Chinese and Their Relatives (2018); Fellow Award of the International Bioprocessing Association and Fellow, Tokyo Institute of Technology (2019); First Prize of Technological Invention, China National Light Industry Council (2019); Collaborative Innovation Elite Award (2020); Special Prize of the Innovation Zhaoqing Science and Technology Award (2021); Second Prize of Science and Technology Progress Award (2022); Outstanding Contribution to Carbohydrate Drugs Award of the Zhang Tianmin Glycodrug Award (2023).


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